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the mean difference (MD) of NAC's effect was −0.43 with a 95% confidence interval (CI), −0.81, −0.04) and lactate concentrations after exercise ( p = 0.03

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However, in light of the myriad of studies describing a link between methionine deficiency and NAFLD, side-effects of interventions targeting the methionine cycle for long-term methionine deprivation should perhaps be approached with caution