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N-Acetylglutamic acid - Wikipedia

P2Y(12) receptors in platelets and other hematopoietic and non-hematopoietic cells

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Much to our delight, however, the introduction of the electron-withdrawing substituent CF 3 (catalyst ( R )- 1d ) and C 2 F 5 (catalyst ( R )- 1e ), rather than the iodo-substituent of ( R )- 1c at the 3,3′-position of the binaphthyl scaffold, resulted in a nearly complete conversion after the same reaction time, with excellent enantioselectivities (98% and 94% ee in entries 4 and 6, respectively)