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5a), displayed potent antitumor activity and substantially reduced systemic toxicity in murine models of prostate cancer and acute myeloid leukemia relative to free PROTAC

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Beyond minoxidil, other topical actives have shown promise in combination: copper peptides (Kuceki 2025) demonstrated significant results in resistant cases, platelet-rich plasma (PRP) has been studied in network meta-analyses, and GHK-Cu serums work through complementary mechanisms