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[DOI] [PMC free article] [PubMed] [Google Scholar] [131].Feng Y, Park H, Bauer L, Ryu JC, Yoon SO, Thiophene-pyrazolourea derivatives as potent, orally bioavailable, and isoform-selective JNK3 inhibitors, ACS Med

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Although thioredoxin-(TRx-) and GSH-dependent pathways have overlapping functions in plants [117,118], Mhamdi and co-workers (2010) demonstrated no upregulation of TRx-dependent genes in increased H 2 O 2 conditions like cat2 and gr1cat2 , providing evidence that GR1 plays a specific role in intracellular H 2 O 2 metabolism