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The outcome suggested that a “transient and limited increase in gut permeability” compared with the “unregulated breach of the gut barrier function due to the TJ deregulation and epithelial cell apoptosis” can rather lead to a dominant regulatory immune response to gut microbiota antigens and to a net anti-inflammatory effect

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Although the findings are preliminary there is evidence emerging from clinical trials to indicate that delta-9-THC and CBD (alone or in combination) can help alleviate various forms of pain, e.g., neuropathic pain, inflammatory pain, and pain associated with MS