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Folate deficiency leads to the accumulation of homocysteine which is associated with an increased risk of cerebrovascular diseases, depression, and dementia, with a focus on vascular dementia and Alzheimer’s disease (4, 20, 22)

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Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling