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The latest one (clinicaltrials.gov identifier: NCT00095355) was designed to examine whether lithium, given alone or with divalproex, increases BDNF levels in the cerebrospinal fluid of HD patients

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It has been established that a number of key processes relating to extracellular inflammatory and fibrotic reaction mediators are involved in PD, although numerous pathways within the cells have yet to be fully delineated