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Statistical Analysis Analyses of continuous outcomes (using a normal likelihood, identity link, shared parameter model) and dichotomous outcomes (using a binomial likelihood, logit link model) feasible for assessment were implemented in WinBUGS (MRC Biostatistics Unit, Cambridge, UK) [32] using a Bayesian approach involving the formal combination of a prior probability distribution and a likelihood distribution, and three Markov Monte-Carlo chains (10,000 iterations)