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As support to a reduced immune performance in the absence of PQQ, neonates from female mice fed with diets devoid of PQQ tend to have reduced levels of interleukin 2, an autocrine and paracrine growth factor important for T-cell proliferation (Steinberg et al., 1994)

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Spatiotemporal Dynamics of Molecular Pathology in Amyotrophic Lateral Sclerosis