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Carnitine metabolism in the vitamin B-12-deficient rat

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Concerning the regulation of GSH-dependent posttranslational modifications of cysteine residues of the proteins involved in the MAPK-signaling pathways, it can be noted that under the oxidative stress caused by menadione (2-methyl-1,4-naphthoquinone), S-glutathionylation of Cys1238 in the ATP-binding domain of MEKK1 inhibits the activity of the kinase [73]