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General clinical guidance often includes: – Dividing the dose (for example, morning and evening) to improve tolerance – Taking NAC away from food if tolerated, as absorption may be better on an empty stomach – Using NAC as part of a long-term strategy , since its benefits are related to ongoing antioxidant and anti-inflammatory support Some research protocols have used NAC cyclically (such as several days per week), while others use daily dosing

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[DOI] [Google Scholar] Yu Y., Yang L., Yin P., Zhou W., Tian L., Yongjian L., et al